When teaching smokers about starting nicotine gum to aid in smoking cessation, tell them to:

Choosing to instruct smokers to chew nicotine gum until they experience a peppery taste or tingling sensation, then placing it in the buccal mucosa, aligns with the effective use of nicotine replacement therapy. The pharmacological mechanism of nicotine gum is designed to release nicotine gradually, which helps alleviate withdrawal symptoms and cravings associated with quitting smoking.

By chewing the gum to the point of taste or sensation, users can activate the nicotine release properly. Storing the gum in the buccal area allows for optimal absorption through the mucosal membranes, which can enhance the effectiveness of nicotine delivery into the bloodstream. This method not only helps manage cravings but also provides a more controlled approach to nicotine intake, facilitating a smoother transition away from smoking.

In contrast, chewing the gum like regular gum may lead to less effective absorption since it bypasses the technique needed for proper nicotine release. Drinking coffee before using the gum is not substantiated as a helpful practice for nicotine absorption, as it could potentially interfere with the medication's intended action. There are also specific guidelines for the frequency and use of nicotine gum that differ from simply chewing one piece every four hours, which can lead to misuse or potentially an excess intake of nicotine. Thus, the guidance provided in the correct answer promotes the